The Paediatric HIV Treatment Optimization is designed to support clinicians to optimize antiretroviral treatment outcomes, identify important drug-drug-interactions based on available best-practice recommendations and clinical guidelines. It also provides an intuitive tool to track and monitor child growth and development. Paediatric HIV Treatment Optimization is available as a web application or hybrid mobile application allowing quick and on-demand reference for ARV dose calculation and optimization.
DisclaimerThe content of this application is intended for education and instruction of qualified health care professionals ONLY. The content presented in this application is no substitute for the clinical judgment of healthcare professionals using this application. Healthcare professionals are encouraged to consult their local authoritative clinical guideline as well as using their best medical judgment in determining appropriate patient care.
For situations which are not be fully covered by this application as provided by Paediatric HIV Treatment Optimization, it is strongly recommended that further information and advice be sought before a clinical decision is made. To the extent permitted by law, Paediatric HIV Treatment Optimization excludes all liability for any injury, loss or damage caused by reliance on any of the information contained in, or provided through the application. The Paediatric HIV Treatment Optimization shall not be held liable for any use of this application. While all reasonable efforts to ensure that the information provided to Paediatric HIV Treatment Optimization from the third parties are correct and up to date, Paediatric HIV Treatment Optimization cannot guarantee complete accuracy of this information and assumes no legal liability or responsibility for the accuracy, currency or completeness of any information from third parties found in this application.
Resources and References:Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV: interim guidelines. Supplement to the 2016 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Geneva: World Health Organization; 2018 (WHO/CDS/HIV/18.51). Available at: https://apps.who.int/iris/handle/10665/277395.
Department of Health and Human Services. Panel on Antiretroviral Guidelines for the Use of Antiretroviral Agents in Paediatric HIV Infection. Available at: https://aidsinfo.nih.gov/guidelines.
The 2019 Paediatric European Network for Treatment of AIDS (PENTA ) guidelines for first and second-line antiretroviral treatment. Available at: https://penta-id.org/hiv/treatment-guidelines/.
World Health Organization child growth standards.: Length/Height-for-Age, Weight-for-Age, Weight-for-Length, Weight-for-Height and Body Mass Index-for-Age; Methods and Development. WHO Press; 2006. Available at: https://www.who.int/childgrowth/standards/en/.
Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids, Res. 2017 Nov 8.